Dosing
Wegovy pill dosage chart and daily instructions
Daily oral Wegovy has an administration routine that matters as much as the tablet strength. It is a prescription treatment, not an over-the-counter substitute for an injection.
The daily tablet schedule
The label starts with 1.5 mg daily for 30 days, then 4 mg daily for 30 days, then 9 mg daily for 30 days, followed by the recommended 25 mg daily maintenance dose. Lower strengths introduce treatment rather than representing the recommended maintenance dose.
If you struggle with a step, ask the clinician how to proceed. Tablet escalation should not be rushed to chase a trial result, and a previous injectable dose does not authorize skipping the initiation schedule. The label contains specific switching instructions that a prescriber must apply.
| Period | Daily tablet |
|---|---|
| Days 1–30 | 1.5 mg |
| Days 31–60 | 4 mg |
| Days 61–90 | 9 mg |
| From day 91 | 25 mg maintenance, as prescribed |
Sources: Wegovy prescribing information, including tablets and Wegovy HD
Morning routine and missed tablets
Swallow the tablet whole with up to 4 ounces of water in the morning on an empty stomach. Do not crush, chew, dissolve, or split it. Wait at least 30 minutes before breakfast, coffee, other beverages, or other oral medicines.
If a daily tablet is missed, skip it and take the next scheduled tablet the following day. Do not double the dose. Discuss a consistent routine and the timing of other medicines with a pharmacist, especially medicines requiring their own fasting schedule.
Sources: Wegovy prescribing information, including tablets and Wegovy HD
Different from Rybelsus and compounded oral products
Oral Wegovy and Rybelsus are separately labeled products. A compounded oral semaglutide product has not passed FDA review as a generic equivalent and cannot borrow the approved product's absorption or clinical evidence.
Your clinician should assess contraindications, other medicines, pregnancy plans, and whether the fasting routine is practical. Tablets are not automatically safer than injections, and the current Wegovy label advises against breastfeeding during tablet treatment.
Sources: Wegovy prescribing information, including tablets and Wegovy HD · Rybelsus and Ozempic tablets prescribing information · FDA concerns with unapproved GLP-1 drugs used for weight loss
Safety before any dose change
These medicines have boxed warnings about thyroid C-cell tumors observed in rodents; whether the same risk occurs in humans is unknown. Personal or family history of medullary thyroid carcinoma or MEN 2 is a contraindication. This is different from saying that every thyroid condition prevents treatment.
Review severe stomach problems, previous pancreatitis, gallbladder disease, kidney problems, diabetes-related eye disease, pregnancy plans, and all medicines with your prescriber. Insulin or sulfonylureas can increase the risk of low blood sugar when combined with these treatments. Vomiting and diarrhea can cause dehydration and kidney injury.
Severe persistent abdominal pain, inability to keep fluids down, or signs of an allergic reaction require prompt medical assessment. Do not increase a dose to overcome slow weight loss or copy another person's prescription. Tell the anesthesia team about treatment before procedures because delayed gastric emptying can affect aspiration risk.
Sources: Wegovy prescribing information, including tablets and Wegovy HD · Ozempic prescribing information · Zepbound prescribing information · Mounjaro prescribing information
Sources and evidence
Sources checked October 2, 2026. Prescribing information supports medication facts; provider pages support advertised services. Offers and labels can change.